Project leader: AI. Developed the conception and design of the study: AI. Project management: BA. Contributed biometric/statistical expertise: GG K-HJ.

Contributed to the study design and methodology: RE K-HJ SM. Guarantors of the Heinz Nixdorf Research Study: RE K-HJ SM. Contributed clinical expertise: BN CH JK. Reviewed the manuscript and made substantial contributions to subsequent drafts: BA BH SP NP US RE K-HJ JK BK BN CH GG SM AI. Java Real Football 2013.

Approved the final manuscript: BA BH SP NP US RE K-HJ JK BK BN CH GG SM AI. Conceived and designed the experiments: BA BH SP NP US RE K-HJ JK BK BN CH GG SM AI.

To address depressive symptoms we used the 'Allgemeine Depressionsskala' (ADS, German version of the Centre for Epidemiologic Studies Depression Scale) (Radloff, 1977). Corel Videostudio Pro X8 Free Download Full Version 32-bit. The ADS ranges from 0 to 60 with a score ≥16 being regarded as clinically significant. The control group for questionnaire.